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Bacterial Mutation Renders Whooping Cough Vaccine Ineffective
pine Webmaster of Pineapple
2012/09/14 07:24
508 topics published
September 13, 2012 (CNA, Reporter Long Ruiyun, Taipei)

Foreign reports indicate that the effectiveness of the whooping cough vaccine diminishes year by year after vaccination. Infectious disease specialist Huang Limin stated today that this may be due to bacterial mutations causing the vaccine to lose efficacy rapidly.

Nicola Klein, a researcher at the Kaiser Permanente Vaccine Study Center, conducted a study on the whooping cough vaccine and found that after the fifth dose, the vaccine's protective effect declines by 40% annually. The findings were published in the online edition of the *New England Journal of Medicine (NEJM)*.

Klein suggested that whooping cough prevention strategies should be reconsidered to avoid future outbreaks. She recommended developing a new whooping cough vaccine or modifying the current formula to provide longer-lasting immunity.

Zhou Zhihao, Deputy Director of the Centers for Disease Control under Taiwan's Department of Health, stated today that newborns receive the "Diphtheria, Tetanus, and acellular Pertussis (DTaP) vaccine" at 2, 4, and 6 months, 18 months, and in the first grade of elementary school.

Zhou noted that while the acellular vaccine has fewer side effects, it elicits a weaker immune response, and antibody levels decline over time. As the study suggests, the risk of whooping cough infection increases each year after vaccination.

Huang Limin, Director of Pediatric Infectious Diseases at National Taiwan University Hospital, pointed out that the whooping cough vaccine loses effectiveness faster than expected, indicating possible bacterial mutations.

Huang emphasized that the vaccine still provides protection, and newborns should continue to receive it according to the recommended schedule. He also suggested administering a sixth booster dose in the later years of elementary school. For adults, he recommended a booster every 10 years and called for adjustments to the vaccine formula.

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