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Study: IVF Stillbirth Rate 4 Times Higher Than Other Conception Methods
pine Webmaster of Pineapple
2010/02/25 13:15
508 topics published
Update Date: 2010/02/24 (AFP Paris 24th)

A new study released today in Denmark shows that women who undergo in vitro fertilization (IVF) treatment have a stillbirth rate four times higher than those who conceive naturally or through other fertilization methods.

The study's authors noted that the reason for this discrepancy remains unclear, but they emphasized that in reality, the risk of stillbirth for IVF couples is relatively low.

The research, led by Kirsten Wisborg from Aarhus University in Denmark, analyzed data from 20,166 first-time single births between 1989 and 2006.

Among these, 82% of the babies were conceived within a year, indicating that the parents were classified as having normal fertility. 10% of the babies were conceived after more than a year of trying, placing them in the subfertile category.

Another 4% of the babies were conceived through IVF or intracytoplasmic sperm injection (ICSI), a technique where a single sperm is injected directly into an egg.

The remaining 4% were born to women who received non-IVF or non-ICSI treatments, such as surgery for blocked fallopian tubes or hormone therapy to restore ovulation.

The stillbirth rate for pregnancies conceived through IVF or ICSI was 16.2 per 1,000, compared to 2.3 per 1,000 for non-IVF treatments, and 3.7 and 5.4 per 1,000 for normal and subfertile couples, respectively.

After accounting for factors that could influence the data, including maternal age, smoking habits, alcohol and coffee consumption, and other variables, Wisborg found that women who conceived through IVF or ICSI had a fourfold higher risk of stillbirth.

No differences in stillbirth rates were observed among the other groups. She stated: "This may suggest that infertility itself is not the cause of the increased stillbirth risk. Instead, other unexplained factors, such as the techniques involved in IVF and ICSI or physiological differences in couples requiring these treatments, may be responsible."

The study was published in the journal *Human Reproduction*, which is published by the European Society of Human Reproduction and Embryology (ESHRE). (Translator: Lin Qianyi, Central News Agency)

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