Study Links High-Starch Diet to Pancreatic Cancer Risk
pine Webmaster of Pineapple
2009/01/10 23:47
508 topics published
Source: Dana-Farber Cancer Institute
Date: 9/4/2002
Research shows a strong correlation between high-starch diets and pancreatic cancer.
Boston — High-starch diets, such as those rich in potatoes, rice, and white bread, may increase the risk of pancreatic cancer in women who are overweight or physically inactive, according to a study conducted by the Dana-Farber Cancer Institute, Brigham and Women's Hospital, and the Harvard School of Public Health.
The report was published in the September 4 issue of the medical journal *Journal of the National Cancer Institute*. The study suggests that insulin, a substance the body uses to process sugar from food, may promote the development of pancreatic cancer.
In the United States, nearly 30,000 men and women are diagnosed with pancreatic cancer each year, and a similar number die from the disease. Pancreatic cancer is highly aggressive and one of the most difficult cancers to treat. Once diagnosed, only 4% of patients survive beyond five years.
Previous research has revealed that insulin promotes the growth of pancreatic cancer cells. Some reports also indicate that obesity, low physical activity, or type 2 diabetes can lead to "insulin resistance," causing individuals to produce more insulin than normal to compensate. However, this excess insulin ultimately places them at a higher risk for pancreatic cancer. The new study further found that women whose diets trigger significant insulin secretion may have an increased risk of developing pancreatic cancer.
The new study discovered that overweight and physically inactive women who consume high-glycemic-load (GL) foods are 2.5 times more likely to develop pancreatic cancer than those who consume low-GL foods. However, lean or physically fit women do not face an increased risk of pancreatic cancer from high-GL foods. Although the study focused on women, researchers believe the same applies to men.
For overweight or inactive women, high-starch foods can increase their risk of pancreatic cancer. Therefore, replacing potatoes and rice with low-starch vegetables like broccoli and substituting snacks with fruits are simple steps to reduce the risk of the disease.
**2002 China Times News**
**Overweight and Starch-Loving Individuals Are More Prone to Pancreatic Cancer**
By Yeh Tao-Hung (President and Consultant Physician at M.C.L. in Los Angeles, USA)
Approximately 30,000 people die from pancreatic cancer each year in the United States. Previous reports only linked smoking to an increased risk of pancreatic cancer. However, the latest research indicates that overweight, physically inactive women who consume excessive amounts of high-starch foods are 2.5 times more likely to develop pancreatic cancer than the average person.
According to a study published in the *Journal of the National Cancer Institute*, women who consume large amounts of white bread, white rice, and potatoes daily have a 57% higher risk of pancreatic cancer. If these dietary habits are combined with overeating and lack of exercise, the risk of pancreatic cancer increases to 2.5 times that of others. This is the latest scientific evidence linking "junk food" to a specific type of cancer.
Dr. Fox from Brigham and Women's Hospital's Dana-Farber Cancer Institute and Harvard School of Public Health, who led the study, stated that the findings show overweight and physically inactive women who consume high-starch foods have an increased risk of pancreatic cancer. One simple way to reduce this risk, according to the researchers, is to replace potatoes and rice with low-starch vegetables like broccoli and to choose fruits as snacks.This large-scale study involved 89,000 healthy nurses, with the research team meticulously recording the nurses' diets and other habits, and closely monitoring their health conditions.
According to the study report by Dr. Fox, overweight women with low physical activity and high sugar intake have increased levels of insulin in their bodies, which promotes the growth of pancreatic cancer cells.
Research reports from the researchers indicate that up to one-third of cancers are associated with dietary and lifestyle habits. For example, lung cancer is closely related to smoking, while the consumption of certain fats and red meat may be linked to breast and colon cancers.
Statistics show that pancreatic cancer has a high fatality rate, with a five-year survival rate of about 5% for patients. The main reason is that 80% of patients are diagnosed at a very advanced stage, resulting in a low survival rate.
European and American experts specializing in food carcinogens recently held an urgent meeting in Geneva, announcing the discovery of a suspected carcinogen "acrylamide." The American consumer group "Center for Science in the Public Interest" also published a research report confirming the preliminary experimental findings reported in Geneva. These results indicate that some fried foods, such as fried starches, contain high levels of "acrylamide."
"Acrylamide" is primarily used in the production of plastics and dyes for water purification. Scientists have conducted animal experiments and found that "acrylamide" may be carcinogenic. The Swedish "National Food Administration" published a report stating that certain starch-based foods can produce "acrylamide" when cooked at high temperatures. The World Health Organization also largely supports the Swedish research findings. Dr. Janice Oliver, the head of food safety at the U.S. Food and Drug Administration (F.D.A.), stated that the current focus is to understand how much "acrylamide" is needed to potentially affect human health.
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