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Study: Household Dust Makes You Fat! Just 3 Micrograms A Day Boosts Fat Cell Growth
pine Webmaster of Pineapple
2017/07/23 14:57
508 topics published
Good Morning Health
Compiled by Chen Jianfu
July 23, 2017

We often say that being lazy and loving good food can make people gain weight. However, besides obesity caused by reduced physical activity, a recent study published in the American Chemical Society (ACS) journal *Environmental Science & Technology* points out that neglecting household cleaning and allowing dust to accumulate is also a key factor in weight gain.

**Endocrine Disruptors in Dust Are the Key to Weight Gain**
This study was conducted by Duke University in North Carolina, USA. As early as 2015, the research team noted that dust contains multiple endocrine-disrupting chemicals that can lead to weight gain. When inhaled, these chemicals can trigger fat cell proliferation and affect the body's fat metabolism rate. Particularly, children exposed to dust during their developmental years face a significantly higher risk of obesity in adulthood. Now, further research has revealed that dust in most households can stimulate the proliferation of 3T3-L1 preadipocytes or catalyze their transformation into mature fat cells, storing triglycerides.

**Only 1 Out of 11 Households Had Dust That Did Not Affect 3T3-L1 Cells**
The research team collected dust from 11 households in North Carolina, extracted 44 endocrine-disrupting chemicals from the dust, and introduced them into 3T3-L1 cells from experimental mice. The results showed that dust extracts from 7 households could mature these preadipocytes and convert them into mature fat cells, while extracts from 9 households caused significant proliferation of preadipocytes. Only one household's dust extract had no effect on the preadipocytes.

**Pesticides, Flame Retardants, and Plasticizers Can All Increase Fat Cells**
The research team explained that endocrine disruptors are commonly found in household appliances, electrical wires, and building materials, such as flame retardants, phthalates, and bisphenol A. Among the 44 endocrine disruptors studied, the three chemicals most responsible for increasing fat cells were pyraclostrobin (a pesticide component), TBPDP (a flame retardant), and dibutyl phthalate (a plasticizer used in glue, nail polish, and other inks). Although their use has been reduced in industrial production, they remain prevalent in many household products.

**Just 3 Micrograms Can Have an Impact—Frequent Cleaning Is Key**
The team calculated that inhaling just 3 micrograms of dust daily can affect 3T3-L1 cells. According to the U.S. Environmental Protection Agency, young children alone are exposed to about 50,000 micrograms of household dust each day. Therefore, frequent cleaning and maintaining a dust-free environment are crucial steps to safeguarding family health and preventing obesity.

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