Excessive Weight Loss in Adolescence Leads to Osteoporosis
2006/05/02 06:34
14 topics published
2006-3-27
Experts from Nagoya University in Japan have published the latest research findings: excessive weight loss during adolescence can lead to osteoporosis.
The research team led by Yasuo Kitagawa proposed that "mesenchymal stem cells" with strong differentiation ability contained in adipose tissue play an important role in bone formation during youth growth. The team examined the adipose tissue of 80 individuals of different age groups and found that the cells in "mesenchymal stem cells" that can differentiate into bone tissue
peak sharply between the ages of 12 and 19 and then decrease rapidly . The bone mass of females reaches its maximum during this age range and then remains at a certain level. The research team concluded that bone formation is not only influenced by bone cells but also that "mesenchymal stem cells" in adipose tissue may play a very important role.
Common methods to prevent osteoporosis include increasing calcium intake and engaging in more physical activity. Professor Kitagawa's research findings will have a significant impact on the weight-loss practices of adolescent girls. Professor Kitagawa warns that excessive weight loss in young women can lead to insufficient bone development, posing a risk of osteoporosis in middle age.
"Mesenchymal stem cells" have strong differentiation abilities. In addition to forming osteoblasts, the basic tissue for bone formation, they can also differentiate into chondrocytes, adipocytes, and myoblasts. The research team selected "mesenchymal stem cells" from adipose tissue for differentiation in a culture medium. The experimental results confirmed that the differentiation ability of "mesenchymal stem cells" gradually declines with age.
Source:
http://www. takungpao. com/ news/ 06/ 03/ 27/ GY- 544020. htm