Clipping Board » Drug Poisoning ─ It is necessary to be aware of the toxic side effects before taking medication.
Antibacterial Chemical Disrupts Hormone Activities
http://www. physorg. com/ news116344966. html
http://www. news. ucdavis. edu/ search/ news_detail. lasso? id=8456
December 08, 2007
A new study from UC Davis has confirmed that an antibacterial chemical commonly added to bath soaps can alter hormone activity in rats and human cells in the laboratory—and does so through a previously unreported mechanism.
These findings add to a growing body of research—both in laboratory animals and humans—that reveals certain synthetic chemicals in household products can cause health problems by interfering with normal hormone functions.
Known as endocrine disruptors or endocrine disrupting substances (EDS), such chemicals have been linked in animal studies to a variety of issues, including cancer, reproductive failure, and developmental abnormalities.
This is the first hormone study to investigate the hormonal effects of the antibacterial compound triclocarban (also known as TTC or 3,4,4'-trichlorocarbanilide). Triclocarban is widely used in household and personal care products, including soaps, body washes, makeup removers, wipes, and detergents. Products containing triclocarban have been widely sold in European and American markets for over 45 years; it is estimated that 1 million pounds of triclocarban are imported into the U.S. market annually.
Researchers discovered two key effects: in human cells in the laboratory, triclocarban enhances the expression of certain genes that are typically regulated by testosterone. Moreover, when male rats were fed triclocarban, organs related to testosterone, such as the prostate, showed abnormal enlargement.
Additionally, the researchers noted that their discovery of triclocarban's hormone-enhancing effects is novel. Previous studies on endocrine disruptors found that they typically act by blocking or reducing hormone effects.
"This finding may ultimately explain some previously described increases in reproductive problems that have been difficult to understand," said co-author Bill Lasley, a reproductive toxicology expert and emeritus professor of veterinary medicine at UC Davis. More research on antibacterial agents and hormone effects is being planned, he said.
Consumers should not use this study as a guide on whether to use products containing triclocarban, Lasley said. "Our mothers taught us to wash our hands well before antibacterial soaps existed, and doing just that can prevent the spread of disease."Source: http:/ / only- perception. blogs……/ 2007/ 12/ blog- post_6539. html
Study: Antimicrobial Chemicals Disrupt Hormonal Activity
http://www. physorg. com/ news116344966. html
http://www. news. ucdavis. edu/ search/ news_detail. lasso? id=8456
December 08, 2007
A new study from UC Davis has confirmed that an antibacterial chemical commonly added to bath soaps can alter hormone activity in rats and human cells in the laboratory—and does so through a previously unreported mechanism.
These findings add to a growing body of research—both in laboratory animals and humans—that reveals certain synthetic chemicals in household products can cause health problems by interfering with normal hormone functions.
Known as endocrine disruptors or endocrine disrupting substances (EDS), such chemicals have been linked in animal studies to a variety of issues, including cancer, reproductive failure, and developmental abnormalities.
This is the first hormone study to investigate the hormonal effects of the antibacterial compound triclocarban (also known as TTC or 3,4,4'-trichlorocarbanilide). Triclocarban is widely used in household and personal care products, including soaps, body washes, makeup removers, wipes, and detergents. Products containing triclocarban have been widely sold in European and American markets for over 45 years; it is estimated that 1 million pounds of triclocarban are imported into the U.S. market annually.
Researchers discovered two key effects: in human cells in the laboratory, triclocarban enhances the expression of certain genes that are typically regulated by testosterone. Moreover, when male rats were fed triclocarban, organs related to testosterone, such as the prostate, showed abnormal enlargement.
Additionally, the researchers noted that their discovery of triclocarban's hormone-enhancing effects is novel. Previous studies on endocrine disruptors found that they typically act by blocking or reducing hormone effects.
"This finding may ultimately explain some previously described increases in reproductive problems that have been difficult to understand," said co-author Bill Lasley, a reproductive toxicology expert and emeritus professor of veterinary medicine at UC Davis. More research on antibacterial agents and hormone effects is being planned, he said.
Consumers should not use this study as a guide on whether to use products containing triclocarban, Lasley said. "Our mothers taught us to wash our hands well before antibacterial soaps existed, and doing just that can prevent the spread of disease."Source: http:/ / only- perception. blogs……/ 2007/ 12/ blog- post_6539. html